A Review on Nose-to-Brain Drug Delivery
نویسندگان
چکیده
Intranasal route of administration shows potential for delivery of drugs to brain. The nose-to-brain drug delivery of drugs is advantageous as it requires low dose of drug, avoids first pass effect. Also it is fast in action and suitable for the drugs that degrade in gastrointestinal tract. Nose-to-brain delivery also avoids blood brain barrier which is important factor to be considered in formulation of CNS targeting drugs. This route of administration is also non-invasive, painless and useful in emergency
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